After learning from Gengai that Tama has been infected by a computer virus, the Odd Jobs trio launch “Operation Midget” and enter Tama’s body to eradicate the virus. Inside, they find an injured man dressed in a white body suit who begs them to deliver a message to the king. Arriving at the Leukocyte Kingdom, the gang finds the place filled with RPG-themed shops such as weapon stores, inns, and casinos. The group decides to enjoy this RPG-like world by playing at the casino and visiting the church to save their game. Joined by Tama’s avatar, Gintoki and the gang head out in search of the Leukocyte King. Let the adventure to destroy the computer virus begin!